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Research Associate in vivo (Ocular)

Date: Dec 5, 2018

Location: Philadelphia, PA, US

Company: Spark Therapeutics

Join the Spark Team


We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable – until now.


We don’t follow footsteps. We create the path.


The In Vivo research associate will be responsible for overseeing and performing in vivo studies to support the ocular team and other therapeutic areas of the translational department.

Additional responsibilities include but are not limited to:

  • Maintain mouse breeding colonies.
  • Scheduling and following multiple concurrent studies according to the experimental design.
  • Perform Intravitreal/Subretinal injections in mice, monitor animal health, collect blood samples, perform necropsies and record data.
  • Perform Electroretinography, OCT and OKR monitoring in injected animals.
  • Interact with ocular team scientists and provide constant feedback.
  • Work cross-functionally with liver and CNS team and provide support to other R&D in vivo needs



  • Perform in vivo experiments and animal monitoring according to applicable regulations in support of the Ocular team and other therapeutic areas.


  • Maintain accurate record of procedures and provide results/comments to study directors


  • Prioritize and plan projects and workloads, manage resources and scheduling. Write and review animal protocols for IACUC approval.


  • Strong organizational skills.
  • Excellent record keeping.
  • Excellent writing and verbal communication skills.


  • Bachelor’s degree/MS in relevant field required and 5+ years of hands on experience with rodents.
  • Advanced skills on handling, restraining, dosing and performing a variety of procedures on study animals required.
  • Ability to manage large mouse colonies required.
  • Excellent organizational, communication and collaborations skills.
  • Keep accurate records, follow instructions and comply with company policies.
  • Experience with Gene Therapy is a plus

Nearest Major Market: Philadelphia

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