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Research Associate

Date: Jan 20, 2022

Location: Philadelphia, PA, US, 19104

Company: Spark Therapeutics

Join the Spark Team


We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable – until now.


We don’t follow footsteps. We create the path.

The Research Associate will normally receive instructions on routine work and instructions on new assignments and may provide guidance to more junior team members.

The Research Associate will participate in molecular assay development and analysis of samples to support multiple preclinical studies for advancing gene therapy programs across all therapeutic areas. S/he will assess bio distribution and transgene under the guidance and supervision of senior scientists and manager.

The primary duties include:

1.            Sample preparation and extraction of DNA and RNA using manual and automated methods.

2.            Assist qPCR assay development and run qPCR analysis following established SOP.

3.            Present in lab meetings and attend cross-team meetings, assist in project tracking and management.

4.            Follow company policies, training programs, quality system and developing good lab skills.

5.            General lab work such as lab maintenance, operation related tasks assigned by supervisor.


Assist in qPCR assay development and analysis of samples

Sample preparation and extraction of DNA and RNA

General lab tasks assigned by supervisor 

Education and Experience Requirements

BA/BS in biological sciences preferred. Generally, has 0-3 years of relevant experience

Key Skills, Abilities, and Competencies

Good learning skills including following instructions, paying attention to details and good documentation are essential.

1.            Knowledge implementing and troubleshooting experiments

2.            Ability to critically analyze problems, develop potential solutions and evaluate impact to the research organization

3.            Ability to assume independent ownership of protocols and experiments

4.            Advanced technical lab skills

Complexity and Problem Solving

                Refer to established procedures and policies

                Worked is performed under general direction

                Participates in determining objectives of assignment

                Plan schedules and arranges own activities in accomplishing objectives

                Work is reviewed upon completion for adequacy in meeting objectives

                Good understanding and application of principles, concepts, practices, standards

Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location.  Accommodations may be made in accordance with applicable law.

Nearest Major Market: Philadelphia