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Research Associate

Date: Mar 29, 2021

Location: Philadelphia, PA, US

Company: Spark Therapeutics

Join the Spark Team


We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable – until now.


We don’t follow footsteps. We create the path.

Primary Duties

Immunology Group within Translational Research Department uses traditional and cutting-edge technology to ensure the safety of all therapeutic strategies at Spark. It is also responsible for the proof-of-concept studies design and execution for treatment of autoimmune diseases, choice of autoimmune indications and establishing the candidate development strategy from Research to Preclinical stage. The successful candidate’s primary responsibility will be to, in collaboration with other team members, propose, design, plan and coordinate execution of in vivo and in vitro studies with the goal of advancing autoimmune disease programs.

The Research Associate is going to be a member of Autoimmunity Team in Immunology Group within the Translational Research Department. He/She will be responsible for:

•     Performing cell culture (primary and cell lines) and execution of cell-based immunoassays

•      Carrying out ELISA, MSD, enzymatic activity and QPCR assays with high scientific quality

•      With guidance from scientists/the lead, implementing new assays or optimizing existing ones

•      Providing summaries of data to scientists and the lead

•      Maintain accurate, timely and detailed records of work (ELN)



% of Time

Job Function and Description


Design, planning, execution, and reporting of bioanalytical/immunological assays including cell-based assays


Data analysis, review, discussion and recording in form of study reports and/or presentations


Implementation of new technologies, assay development and optimization


Performance of cross-functional projects to support Immunology Group at large

Education and Experience Requirements



  • Bachelor’s degree in a relevant life sciences field such as cell biology, molecular biology, biochemistry, immunology, virology, or genetics/genomics. Master’s degree is a plus.
  • 3+ years of relevant hands-on experience in laboratory. Industry experience and familiarity with GLP is a plus.


Key Skills, Abilities, and Competencies

  • Ability to work independently and as a part of a team in hands-on laboratory setting, eager to learn, explore and develop new techniques
  • Able to perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies
  • Adaptable with a positive attitude, excellent organizational and communication skills
  • Experienced in general and advanced laboratory techniques such as for example qPCR, RT-qPCR, ELISA, cell culture, IPSCs generation, culture and differentiation, plate-based reporter and/or enzymatic activity assays, flow cytometry

Nearest Major Market: Philadelphia