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Research Associate

Date: Aug 14, 2019

Location: Philadelphia, PA, US

Company: Spark Therapeutics

Join the Spark Team


We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable – until now.


We don’t follow footsteps. We create the path.


The Research Associate is a member of the Liver Research Group within the Translational Research Department and will support the Liver Research Group in laboratory research activities towards development and testing of novel gene therapy products. He/she will be responsible for:


  • Performance of routine assays across the different liver research group pipeline programs (e.g. molecular cloning, ELISA, qPCR, western blot, etc).
  • Analysis and accurate documentation of assay results in an electronic lab notebook, technical documents and other reporting formats.
  • Assist with the development and implementation of new assays (e.g. cell-based, enzymatic, immunoassays, etc.) or optimization of existing assays based on in-depth knowledge of laboratory techniques.

Plan, prepare and perform experiments on the bench to support of the Liver Research Group pre-clinical programs. Assist technical staff in the performance of laboratory experiments as needed.

Prepare sample analysis reports and accurately document work in electronic lab notebook.

Participate in group meetings and scientific discussions/troubleshooting.

  • BA/BS in biological sciences required. Master’s degree preferred
  • Generally, has 3-5 years of relevant experience
  • Strong understanding of the technical and equipment needs in a lab as well as significant hands-on experience with standard molecular and cell biology techniques such as DNA cloning, qPCR, ELISA, cell culture, transfection, western blotting, etc.
  • Experience with AAV vectors is a plus.
  • Experience in general and advanced lab techniques such as molecular cloning and plasmid design and construction, qPCR, ELISA, cell culture, plate-based luciferase and/or enzymatic activity assays, SDS-PAGE/western blotting, etc.
  • Proven ability to work independently in hands-on laboratory setting, self-motivated to learn and develop new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.
  • Familiarity of Electronic Lab Notebook (ELN) and Laboratory Information Management Systems (LIMS) a plus.
  • Familiar with computer software commonly used in bio/pharma industries.
  • Strong organizational skills.
  • Excellent communication skills (both oral and written).
  • Works with colleagues as a team player.

Nearest Major Market: Philadelphia

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