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Product Manager Lead - LUXTURNA

Date: Jun 10, 2021

Location: Philadelphia, PA, US

Company: Spark Therapeutics

Join the Spark Team


We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable – until now.


We don’t follow footsteps. We create the path.




The Product Manager will report to the US Marketing Team Leader, serving as a brand champion and responsible for assisting in the development and execution of marketing plans that seek to serve the needs of people with inherited retinal disease (IRDs).
The Product Manager drives the development, implementation, integration, and management of strategies, programs, services and tactics for assigned channel(s), customer segment(s) and/or key initiatives in collaboration with other members of the commercial team and relevant internal stakeholders (GDLs, ZLs, DSL). A key focus will be on developing and implementing marketing communications, programs, and resources targeted toward patients and HCPs to drive awareness of gene therapy, genetic testing and brand awareness.  The PM must have a keen understanding of the multichannel marketing experience, including personal and non-personal promotion; digital marketing (SEO/SEM/display); patient activation; training and communication materials for field representatives; and Congress and Conference participation in the ophthalmology space.

Responsible for ensuring quality and timely completion of tactics both independently and with the support of vendors/agencies.  As appropriate, this role requires - vendor/agency management and training, providing clear direction for work delegated to agency partners.

Additional responsibilities will include marketing operations support, management of MSAs/SOWs, generation of POs and monthly budget management and accruals.

As part of the marketing team, this role will share responsibility for achieving revenue and sales targets and will work closely with sales and marketing personnel to develop ideas to

promote the brand and increase its reach. In delivering against assigned objectives, the role collaborates and integrates extensively with other members of the commercial team and multiple cross functional team members. The role also requires flexibility to respond to requests from leadership to support various key projects and initiatives that may arise. 




  • Develop and execute tactics to achieve assigned brand marketing objectives 
  • Develop and execute promotional and service-oriented content for personal and non-personal channels across patient and HCP customers
  • Serve as a key architect of the multichannel marketing experience and provide input/support development for marketing programs and technology platforms
  • Lead the rollout for assigned programs and tactics to ensure they deliver against defined strategies (through clear KPIs).
    • Field comms
    • Training
    • Metrics
  • This includes the routing of programs/tactics through the Commercial, Medical, Legal, Regulatory (CAT) review process, and the development of measurement frameworks and metrics to measure effectiveness 
  • Manage all expiring assets for renewal and make recommendations of what items need to be extended and/or retired
  • Manage the flow and pass through of any data updates or label changes (e.g. 5yr combined durability data)
  • Collaborate with relevant team members to align strategies and programs and ensure ongoing oversight
  • Plan and oversee the implementation of key external meetings, including medical/HCP congresses within the ophthalmology space by identifying, assembling, and coordinating requirements; interfacing with vendors; developing schedules and assignments; and organizing logistics.
  • Plan and manage the internal NSM meeting, collaborating with the GDL organization
  • Budget management – in collaboration with finance, take full responsibility for the tracking, reconciliation and accruals of marketing budget and expenses, ensuring that resources are utilized effectively, efficiently, and compliantly
  • Forecast, develop and manage budgets for marketing initiatives.
  • Manage delivery and execution of all marketing related MSAs/SOWs and generate corresponding POs for payment
  • Marketing Analytics - Help to assess the effectiveness of existing marketing programs and determine ways to increase efficacy. Work with the agency and the Commercial Operations group to make data driven decisions to determine the future of existing projects. Generate reports and status updates for marketing department supervisors and management.
  • Analyze the post Congress data to determine effectiveness of the meeting and be able to quantify the number of qualified leads generated.  Work with Medical on the Congress/Conference follow up.
  • Research market trends and adapt strategies to leverage that information.
  • Assess need for and participation in primary research
  • Develop and maintain positive and collaborative working relationships with a broad range of internal and external stakeholders to ensure achievement of assigned objectives and/or maximize the impact & effectiveness of programs and tactics to achieve those objectives. 
  • Effectively manage relevant vendor, agency and consultant relationships to ensure deliverables and work products are in alignment with the broader brand/commercial strategies
  • Ensure understanding of and adherence to all relevant internal and external policies or guidelines related to the team’s activities and deliverables



Education and Experience Requirements


  • Bachelor’s Degree required, MBA preferred
  • 5years of pharmaceutical/biotech commercial experience and product launch experience preferred
  • 3 years multichannel marketing experience, including digital (SEO/SEM/display), lead generation, web, mobile, social, personal and non-personal promotion and field promotion channels required
  • Previous experience in digital multichannel marketing strongly preferred
  • Experience/knowledge in rare diseases and/or ophthalmologic therapeutic areas preferred
  • Payer marketing experience preferred
  • Demonstrated success in marketing, strategy development, and cross-functional problem solving
  • Understanding of US promotional regulatory environments
  • Domestic travel required
  • Ability to travel overnihgt 20%


Key Skills and Abilities


  • Self-starter who functions well independently or within a team
  • Strong oral and written communication skills required
  • Presentation skills – routinely present ideas and reports to business leaders and other marketing professionals, so excellent public speaking and presentation skills
  • Proven business knowledge of marketing processes, procedures, and deliverables across broad audiences, i.e. MD, RN, Patient, etc.
  • Excellent organizational, prioritization and influence skills, including the ability to work across functions and lead without authority
  • Team coordination – work closely with internal and external cross functional team members; demonstrated experience coordinating and motivating teams to successfully complete projects
  • Proven ability to engage and support the field sales organization in the successful roll-out and implementation of personal marketing tactics.
  • Ability to formulate clear, actionable strategies that capitalize on opportunities for the brand(s)
  • Analytical skills – excellent analytical and data interpretation skills required
  • Ability to deal with ambiguity and make decisions efficiently, even in the absence of perfect information
  • Demonstrated experience in the development and execution of marketing strategies and tactics
  • Proven strong vendor and timeline management, and ability to effectively manage a creative advertising agency with minimal supervision


Nearest Major Market: Philadelphia