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Enterprise Architect Lead

Date: Sep 10, 2022

Location: Philadelphia, PA, US, 19104

Company: Spark Therapeutics

Join the Spark Team


We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable – until now.


We don’t follow footsteps. We create the path.





The Enterprise Architect Lead provides technical and functional knowledge across multiple business areas, with advanced expertise in multiple architecture layers, such as applications, data and integration, infrastructure, cybersecurity, and business processes.  

The Enterprise Architect Lead acts as a trusted advisor for Spark IT Business Partners and the functions they support.  The EA Lead supports the development of technology roadmaps by assessing the impact of proposed solutions across the portfolio and across the architecture layers.  The EA Lead helps propose and evaluate the feasibility of solutions, identifies gaps and opportunities, and recommends alternatives when appropriate.    They help develop, maintain, and leverage the enterprise architecture (EA) blueprints and artifacts across the organization. They are accountable for helping define and mature EA processes (e.g., Architecture Assurance), and for supporting the integration of architectural principles and standards into other related business and IT processes.

They work to develop an integrated view of the enterprise using a practical and effective repeatable approach, cohesive framework, and available industry standard techniques


Support Development of Target and Transition Architectures


  • Assess impact of proposed solutions across other items in the active IT portfolio and longer-term roadmap. 
  • Assess impact of proposed solutions across architecture domains/layers
  • Support Gap & Opportunity Analysis, and help elaborate the definition of roadmap components
  • Leverage functional and technical expertise and understanding of the architecture to recommend solutions, identifying what is and what is not possible
  • When necessary or relevant, recommend transition architectures with defined incremental value towards achieving the target architecture
  • Partner across the organization to establish and maintain roadmaps for each functional area
  • Participate in the analysis and estimation of feasibility, costs, time, and resources needed to implement roadmap components


Architecture Advisory to Project Execution

  • Provide consulting support to project teams, helping to identify the best practices, processes, tools, and technologies across architecture layers, ensuring delivery of a complete solutions set
  • Assure that assigned projects are aligned with the architecture, standards, policies and guidelines, and key IT strategies
  • Effectively anticipate implementation obstacles and develops risk mitigation strategies where appropriate.


Architecture Portfolio Management

  • Document and analyze the baseline architecture across the Application, Data, and Technology domains
  • Participate in the analysis of systems and processes from end-to-end, assessing how data travels and is used from multiple perspectives.
  • Work across functions and project teams to maintain and govern the baseline architecture and roadmaps as changes are introduced


Technical Debt and Health Assessments

  • Propose new technical standards for element(s) of the architecture in area of expertise and develop migration plans to the future technology architecture, including phase out and retirement
  • Participate in and/or lead the evaluation of new technologies relative to area of the architecture expertise
  • Evaluates and selects hardware and software product standards and the design of standard configuration, balancing competing needs of standardization and innovation
  • Participate in maintaining application and technology attributes resulting in portfolio health heatmaps
  • Leverage heatmaps to develop and communicate plans to address technical debt


Architecture Playbook Management

  • Develops, maintains, and communicates processes and standard practices related to the design, development, and implementation of application solutions and patterns
  • Develop/improve standardized models, documentation templates, and job aids that support EA work.  Socialize their use across projects and the EA Community of Practice



Education and Experience Requirements



  • Bachelor’s Degree in business, information systems, industrial engineering or a related field, and extensive relevant project experience
  • 10 years of IT and business/industry work experience including IT Enterprise Architecture design and deployment, business scenario analysis, systems lifecycle management, and program management.
  • Leadership experience in managing multiple, large, cross-functional teams or projects, and influencing senior level management and key stakeholders.
  • Experience in two or more of the following areas in a Life Science Biopharma Manufacturing environment: business transformation and optimization, strategic planning, leadership, business relationship management and business process management.
  • Requires exposure to multiple, diverse technologies and processing environments.
  • Experience with Application Integration within hybrid cloud environments
  • Data Architecture Experience including understanding of Data Governance, Data Warehouse/Lake, Unstructured Data environment, tools, Data Regulations and Standards
  • Strong background and experience driving Application Portfolio simplification
  • Knowledge of all components of holistic enterprise architecture, business re-engineering principles and processes.  Knowledge of architecture framework and methods, such as TOGAF.  TOGAF Level 2 Certification (TOGAF Certified) a plus.
  • Hybrid working arrangement



Key Skills, Abilities, and Competencies


  • Deep knowledge and experience in Life Science Biopharma information management trends and leading practices across the full Life Science value chain
  • Knowledge of existing, new, and emerging technologies and ability to practically apply them to new business designs and business models to achieve targeted business outcomes.
  • Support cross functional teams by providing technical strategy, reference architectures, solution design, interfaces and data flows.
  • Ability to model business capabilities, value streams, business processes, and organizational structures in alignment with business stakeholders and SMEs.
  • Comprehensive knowledge of organization change management concepts.
  • Strong analytical and conceptual skills; ability to create original concepts and theories for a variety of projects
  • Ability to communicate, influence and persuade — both business and IT leaders, as well as peers.
  • Uses the language of business leaders and join the conversation that's taking place.
  • Ability to adapt to rapidly changing technologies and see how they can support business needs.
  • Ability to establish and maintain a high level of stakeholder trust and confidence.
  • Understands business process management, workflow and integration methods and tools
  • Deep knowledge and experience in Information Management and Architecture Design - ability to use appropriate tools and logical models to develop an information architecture to meet company needs
  • Ability to estimate the financial impact of technical architecture alternatives.
  • Communicate effectively with both technical and business individuals at all levels – strong ability to translate information management concepts to business stakeholders in business terms


  • Complexity and Problem Solving


  • Undertakes objective, critical analysis to work through issues, explore different possibilities, and identify the most effective solution that takes account of business context
  • Influences the organization, users, or vendors on architecture decisions
  • Monitors the market to gain knowledge of new and emerging technologies and assess the relevance and potential value to the company
  • Analyzes project needs and determines resources needed to meet objectives and solve problems


Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location.  Accommodations may be made in accordance with applicable law.

Nearest Major Market: Philadelphia